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This literature review examines central diabetes insipidus (CDI) as a rare side effect of temozolomide, a chemotherapeutic agent used for CNS malignancies, with a focus on nine reported cases. CDI manifests as polyuria and polydipsia within 3 to 12 weeks of temozolomide initiation, and while it is typically reversible, the exact pathophysiology remains unclear. The review highlights the need for further research to understand the mechanisms behind CDI in temozolomide-treated patients and its implications fo

Author

Lâm Diễm Trân

Language

EN