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What is Flexible Empirical Bayes Variance Shrinkage about?

The paper introduces a flexible empirical Bayes method called Variance Adaptive Shrinkage (vash) for estimating gene variances in genomic studies, which addresses limitations of the common inverse-gamma distribution assumption. The authors demonstrate that their method can outperform existing approaches when variances are complex, while still providing competitive performance under traditional conditions. The vashr R package is made available for implementation of this method in gene expression analyses.

Author

cuitengfei2021

Language

EN