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Synthesis of P-Nitroacetanilide by ScribdTranslations is a document available to read on EtoBox.
This document describes the synthesis of p-nitroacetanilide through electrophilic aromatic substitution reactions. First, acetanilide is protected by dissolving it in concentrated sulfuric acid. Then, nitration is performed by adding a solution of nitric acid in concentrated sulfuric acid at low temperature. Finally, the protecting group is removed by adding the nitration product to a mixture of water and ice, precipitating p-nitro.
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- EN