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Drug distribution refers to the penetration of a drug to its sites of action through blood vessel walls after absorption, occurring in various body fluid compartments. The apparent volume of distribution (VD) indicates how a drug is distributed in the body relative to its plasma concentration, influenced by factors such as protein binding and plasma concentration. Protein binding affects the active concentration of the drug, with high protein-bound drugs acting longer and low protein-bound drugs acting shor

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fefog15333

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EN