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This study investigates the effects of amlodipine, a calcium channel blocker, and enalapril, an ACE inhibitor, on dependent leg edema in hypertensive men. Amlodipine was found to increase leg weight and blunt postural vasoconstriction, leading to fluid extravasation, while enalapril did not affect leg weight but reduced edema caused by amlodipine. The findings suggest that the combination of these medications may mitigate the side effects associated with calcium channel blockers in treating essential hypert

Author

A4548 99 Irvan Adi Maulana

Language

EN