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Determinants of Quality of Life in Patients with Drug-resistant Focal Epilepsy by Bruno Silva; Hugo Canas-Simião; Susana Cordeiro; Ana Velosa; Albino J. Oliveira-Maia; J. Bernardo Barahona-Corrêa is a Medicine article available to read on EtoBox.
What is Determinants of Quality of Life in Patients with Drug-resistant Focal Epilepsy about?
## Introduction: Focal drug-resistant epilepsy (dre) has been associated with a significant burden of psychiatric comorbidity and low health-related quality of life (hrqol). there is ample disagreement in previous studies as to which factors decisively influence hrqol in this population. here, we sought to assess the relationship between sociodemographic factors, epilepsy-related variables, and psychiatric comorbidity with hrqol in a well-defined group of patients with focal dre. ## Methods: We consecutively recruited a sample of adult patients with confirmed focal dre being considered for epilepsy surgery in a reference center in lisbon, portugal. psychiatric diagnoses were defined according to the mini-international neuropsychiatric interview (m.i.n.i.), and hrqol was measured using the quality-of-life in epilepsy inventory (qolie-31). associations with qolie-31 total score were tested using regression models. ## Results: Among the forty patients included in the study, being diagnosed with a mood disorder was significantly associated with a lower total qolie-31 score (β = -21.18, p = 0.001) in univariate analysis. multivariate analysis additionally identified female gender as a s
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- Author
- Bruno Silva; Hugo Canas-Simião; Susana Cordeiro; Ana Velosa; Albino J. Oliveira-Maia; J. Bernardo Barahona-Corrêa
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)