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Monocular Visual Activation Patterns in Albinism as Revealed by Functional Magnetic Resonance Imaging by Bernd Schmitz; Barbara Käsmann-Kellner; Torsten Schäfer; Christoph M. Krick; Georg Grön; Martin Backens; Wolfgang Reith is a Neuroscience article available to read on EtoBox.
What is Monocular Visual Activation Patterns in Albinism as Revealed by Functional Magnetic Resonance Imaging about?
## Abstract Human albinism is characterized by a disturbance of the chiasmatic projection system leading to predominant representation of just one eye in the contralateral hemisphere. Patients show congenital nystagmus without perceiving oscillopsia. The purpose of the present study was to demonstrate the consequences of atypical chiasmatic crossing with monocular visual stimulation using functional magnetic resonance imaging (fMRI). Sixteen patients with albinism and fifteen normally pigmented controls were stimulated with a monocular visual activation paradigm using flickering checkerboards. In patients, we observed contralaterally dominated activation of visual cortices correlating to clinical albinism parameters. This confirms albinism as a continuous range of hypopigmentation disorders. Additionally, albinos showed activation of the superior colliculus and of visual motion areas although the stimulus was stationary. Activation of visual motion areas is due probably to congenital nystagmus without a conscious correlate like oscillopsia. Hum. Brain Mapping 23:40–52, 2004. © 2004 Wiley‐Liss, Inc.
Who reads Monocular Visual Activation Patterns in Albinism as Revealed by Functional Magnetic Resonance Imaging?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Bernd Schmitz; Barbara Käsmann-Kellner; Torsten Schäfer; Christoph M. Krick; Georg Grön; Martin Backens; Wolfgang Reith
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1065-9471)
- Published
- 2004
- Language
- EN
- Field
- Neuroscience (Life Sciences)