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Treating Brain Disorders by Targeting Adult Neural Stem Cells by Hechen Bao; Juan Song is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Treating Brain Disorders by Targeting Adult Neural Stem Cells about?
Adult neurogenesis, a developmental process of generating functionally integrated neurons from neural stem cells, occurs throughout life in the hippocampus of the mammalian brain and highlights the plastic nature of the mature central nervous system. Substantial evidence suggests that new neurons participate in cognitive and affective brain functions and aberrant adult neurogenesis contributes to various brain disorders. Focusing on adult hippocampal neurogenesis, we review recent findings that advance our understanding of the key properties and potential functions of adult neural stem cells. We further discuss the key evidence demonstrating the causal role of aberrant hippocampal neurogenesis and various brain disorders. Finally, we propose strategies aimed at simultaneously correcting stem cells and their niche for treating brain disorders.
Who reads Treating Brain Disorders by Targeting Adult Neural Stem Cells?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Hechen Bao; Juan Song
- Publisher
- Elsevier BV
- Published
- 2018
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)