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Can I read Vascular and Haemodynamic Issues of Brain Ageing on EtoBox?
Vascular and Haemodynamic Issues of Brain Ageing by Lucy Beishon; Rebecca H. Clough; Meeriam Kadicheeni; Tamara Chithiramohan; Ronney B. Panerai; Victoria J. Haunton; Jatinder S. Minhas; Thompson G. Robinson is a Medicine article available to read on EtoBox.
What is Vascular and Haemodynamic Issues of Brain Ageing about?
The population is ageing worldwide, thus increasing the burden of common age-related disorders to the individual, society and economy. Cerebrovascular diseases (stroke, dementia) contribute a significant proportion of this burden and are associated with high morbidity and mortality. Thus, understanding and promoting healthy vascular brain ageing are becoming an increasing priority for healthcare systems. In this review, we consider the effects of normal ageing on two major physiological processes responsible for vascular brain function: Cerebral autoregulation (CA) and neurovascular coupling (NVC). CA is the process by which the brain regulates cerebral blood flow (CBF) and protects against falls and surges in cerebral perfusion pressure, which risk hypoxic brain injury and pressure damage, respectively. In contrast, NVC is the process by which CBF is matched to cerebral metabolic activity, ensuring adequate local oxygenation and nutrient delivery for increased neuronal activity. Healthy ageing is associated with a number of key physiological adaptations in these processes to mitigate age-related functional and structural declines. Through multiple different paradigms assessing CA
Who reads Vascular and Haemodynamic Issues of Brain Ageing?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Lucy Beishon; Rebecca H. Clough; Meeriam Kadicheeni; Tamara Chithiramohan; Ronney B. Panerai; Victoria J. Haunton; Jatinder S. Minhas; Thompson G. Robinson
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Life Sciences)