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This study investigates the molecular mechanisms behind the synergistic effects of nano-hydroxyapatite (NanoHA) and leukocyte- and platelet-rich fibrin (L-PRF) on osseointegration in osteoporotic conditions using an in vivo model with Wistar rats. Results show that the combination of NanoHA and L-PRF significantly enhances gene expression related to bone metabolism, promoting a favorable environment for osseointegration despite systemic estrogen deficiency. These findings suggest that this therapeutic appro

Author

Nagaraju Akunuri

Language

EN