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The pentose phosphate pathway (PPP) is an alternative route for glucose oxidation that produces NADPH and ribose for nucleic acid synthesis, playing a crucial role in cellular protection against reactive oxygen species. The pathway consists of an oxidative phase that generates NADPH and a non-oxidative phase that converts ribulose-5-phosphate into various sugars. Deficiencies in enzymes such as glucose-6-phosphate dehydrogenase can lead to conditions like hemolytic anemia, highlighting the pathway

Author

Ибргим Абайханов

Language

EN