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Integration of Polymeric Membranes with Microfluidic Networks for Bioanalytical Applications by Pen-Cheng Wang; Donald L. DeVoe; Cheng S. Lee is a Engineering article available to read on EtoBox.

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## Integration of polymeric membranes with microfluidic networks for bioanalytical applications The concept of microfluidics has significantly influenced the design and the implementation of modern bioanalytical systems due to the fact that these miniaturized devices can handle and manipulate samples in a much more efficient way than conventional instruments. In an analogy to the development of microelectronics, increasingly sophisticated devices with greater functionalities have become one of the major goals being pursued in the area of micrototal analysis systems. The incorporation of polymeric membranes into microfluidic networks has therefore been employed in an effort to enhance the functionalities of these microfabricated devices. These commercially available membranes are porous, flexible, mechanically robust and compatible with plastic microfluidic networks. The large surface area-to-volume ratio of porous membrane media is particularly important for achieving rapid buffer exchange during microdialysis and obtaining ultrahigh concentration of adsorbed enzymes for various biochemical reactions. Furthermore, the membrane pore diameter in the sub-mm range eliminates the constr

Who reads Integration of Polymeric Membranes with Microfluidic Networks for Bioanalytical Applications?

Author

Pen-Cheng Wang; Donald L. DeVoe; Cheng S. Lee

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 0173-0835)

Published

2001

Language

EN

Field

Engineering (Physical Sciences)