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Improved Methods for Building Protein Models in Electron Density Maps and the Location of Errors in These Models by T. A. Jones; J. Y. Zou; S. W. Cowan; M. Kjeldgaard is a Materials Science article available to read on EtoBox.

What is Improved Methods for Building Protein Models in Electron Density Maps and the Location of Errors in These Models about?

Map interpretation remains a critical step in solving the structure of a macromolecule. Errors introduced at this early stage may persist throughout crystallographic refinement and result in an incorrect structure. The normally quoted crystallographic residual is often a poor description for the quality of the model. Strategies and tools are described that help to alleviate this problem. These simplify the model-building process, quantify the goodness of fit of the model on a per-residue basis and locate possible errors in peptide and side-chain conformations.

Who reads Improved Methods for Building Protein Models in Electron Density Maps and the Location of Errors in These Models?

Author

T. A. Jones; J. Y. Zou; S. W. Cowan; M. Kjeldgaard

Publisher

International Union of Crystallography (IUCr)

Published

1991

Language

EN

Field

Materials Science (Physical Sciences)