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Asymmetric Synthesis of β-Dialkylamino Alcohols by Transfer Hydrogenation of α-Dialkylamino Ketones by Tomasz Kosmalski; Andrzej Wojtczak; Marek Zaidlewicz is a Chemistry article available to read on EtoBox.

Transfer hydrogenation of representative aryl and heteroaryl dialkylaminomethyl ketones with formic acid-triethylamine, catalyzed by RuCl[(R,R)-TsDPEN](g-p-cymene), produces the corresponding b-dialkylamino alcohols, 97-99% ee, in 50-73% yields.

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Author
Tomasz Kosmalski; Andrzej Wojtczak; Marek Zaidlewicz
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0957-4166)
Published
2009
Language
EN
Field
Chemistry (Physical Sciences)