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Can I read Renal impairment in a rural African antiretroviral programme on EtoBox?
Renal impairment in a rural African antiretroviral programme by Cara Franey; Deborah Knott; Till Barnighausen; Martin Dedicoat; Ahmed Adam; Richard J Lessells; Marie-Louise Newell; Graham S Cooke is a Medicine article available to read on EtoBox.
What is Renal impairment in a rural African antiretroviral programme about?
## Abstract ## Background There is little knowledge regarding the prevalence and nature of renal impairment in African populations initiating antiretroviral treatment, nor evidence to inform the most cost effective methods of screening for renal impairment. With the increasing availability of the potentially nephrotixic drug, tenofovir, such information is important for the planning of antiretroviral programmes ## Methods (i) Retrospective review of the prevalence and risk factors for impaired renal function in 2189 individuals initiating antiretroviral treatment in a rural African setting between 2004 and 2007 (ii) A prospective study of 149 consecutive patients initiating antiretrovirals to assess the utility of urine analysis for the detection of impaired renal function. Severe renal and moderately impaired renal function were defined as an estimated GFR of ≤ 30 mls/min/1.73 m^2^ and 30–60 mls/min/1.73 m^2^ respectively. Logistic regression was used to determine odds ratio (OR) of significantly impaired renal function (combining severe and moderate impairment). Co-variates for analysis were age, sex and CD4 count at initiation. ## Results (i) There was a low prevalence of severe
Who reads Renal impairment in a rural African antiretroviral programme?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Cara Franey; Deborah Knott; Till Barnighausen; Martin Dedicoat; Ahmed Adam; Richard J Lessells; Marie-Louise Newell; Graham S Cooke
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2334)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)