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This article discusses the role and evolutionary history of dystrophins and related proteins in vertebrates and invertebrates, highlighting their critical function in maintaining membrane-associated complexes. It presents sequences of dystrophin-related proteins from various species, including Drosophila melanogaster, and infers that most metazoans possess a single conserved dystrophin-like protein alongside a distinct dystrobrevin. The study suggests that the divergence of dystrophin and utrophin occurred
- Author
- Omowunmi Emmanuel
- Language
- EN