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Can I read In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota on EtoBox?
In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota by Md Abdur Rahim; Hoonhee Seo; Sukyung Kim; Hanieh Tajdozian; Indrajeet Barman; Youngkyoung Lee; Saebim Lee; Ho-Yeon Song is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota about?
__Mycobacterium tuberculosis__ (__M. tb__), the etiological agent of tuberculosis (TB), poses a severe challenge for public health and remains the number one cause of death as a single infectious agent. There are 10 million active cases of TB per year with 1.5 million deaths, and 2–3 billion people are estimated to harbor latent __M. tb__ infection. Moreover, the emergence of multi-drug-resistant (MDR), extremely-drug-resistant (XDR), and the recent totally drug-resistant (TDR) __M. tb__ is becoming a global issue that has fueled the need to find new drugs different from existing regimens. In these circumstances, probiotics can be a potential choice, so we focused on developing them as an anti-tuberculosis drug candidate. Here, we report the anti-tubercular activities of __Lacticaseibacillus rhamnosus__ PMC203 isolated from the vaginal microbiota of healthy women. PMC203 exhibited a promising intracellular killing effect against both drug-sensitive and resistant __M. tb__ infected murine macrophage cell line RAW 264.7 without showing any cytotoxicity. Additionally, it also inhibited the growth of __M. tb__ under broth culture medium. PMC203 did not cause weight change or specific c
Who reads In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Md Abdur Rahim; Hoonhee Seo; Sukyung Kim; Hanieh Tajdozian; Indrajeet Barman; Youngkyoung Lee; Saebim Lee; Ho-Yeon Song
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)