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The study investigates the role of microRNA-146a (miR-146a) in reducing inflammation and reactive oxygen species (ROS) production in aged dermal fibroblasts, which are crucial for skin healing. Findings reveal that aged fibroblasts have lower miR-146a levels and higher NOX4 expression, leading to increased inflammation and ROS. Overexpression of miR-146a significantly decreases these inflammatory responses and ROS production, suggesting its potential as a therapeutic target for improving wound healing in th
- Author
- silvan saputra
- Language
- EN