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Addressing Uncertainty in Mouthing-mediated Ingestion of Chemicals on Indoor Surfaces, Objects, and Dust by Li, Li; Hughes, Lauren; Arnot, Jon A. is a Environmental Science article available to read on EtoBox.

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In indoor environments, humans ingest chemicals present as surface residues and bound to settled particles (dust), through mouthing hands (hand-to-mouth transfer) and objects (object-to-mouth transfer). Here, we introduce a novel modeling approach in support of systematic investigation into the mouthing-mediated ingestion of chemicals present in indoor environments. This model explicitly considers the indoor dynamics of dust and chemicals, building on mechanistic links with physicochemical properties of chemicals, features of the indoor environment, and human activity patterns. The evaluation of this model demonstrates that it satisfactorily reproduces chemical hand loadings and exposure data reported in the literature. We then use the evaluated model to investigate the response of mouthing-mediated ingestion to chemical partitioning between the gas phase and solid phases, expressed as the octanol-air partition coefficient (K). Assuming a unit emission rate to the indoor environment, we find that low-volatility chemicals (with a K greater than 10) are more efficiently enriched in hand skin, resulting in higher mouthing-mediated ingestion than other compounds. For individuals living

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Author

Li, Li; Hughes, Lauren; Arnot, Jon A.

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0160-4120)

Published

2021

Language

EN

Field

Environmental Science (Physical Sciences)