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Tumor Acidosis Drives Splicing Changes by albimar239512 is a document available to read on EtoBox.
This study investigates the role of acidosis in the tumor microenvironment, revealing that acidic regions at the tumor-stroma interface are associated with aggressive tumor phenotypes and altered gene expression. Using a pH-responsive peptide, researchers identified these acidic areas and demonstrated that acidosis influences alternative splicing of key genes involved in invasion and drug resistance. The findings suggest that targeting acidosis may provide new therapeutic strategies for cancer treatment.
- Author
- albimar239512
- Language
- EN