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Tenascin-C by Phurman Lama is a document available to read on EtoBox.
What is Tenascin-C about?
1) This study examines how the extracellular matrix protein tenascin-C (TN-C) affects the development of experimental autoimmune myocarditis. 2) The researchers found that TN-C knockout mice were protected from severe myocarditis compared to wild-type mice. 3) TN-C was found to induce the production of proinflammatory cytokines in dendritic cells through activation of Toll-like receptor 4, leading to increased Th17 cell differentiation and exacerbated myocardial inflammation.
- Author
- Phurman Lama
- Language
- EN