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Albumin Extravasation and Tissue Washout of Hyaluronan After Plasma Volume Expansion with Crystalloid or Hypooncotic Colloid Solutions by S. Berg; M. Golster; B. Lisander is a Medicine article available to read on EtoBox.

What is Albumin Extravasation and Tissue Washout of Hyaluronan After Plasma Volume Expansion with Crystalloid or Hypooncotic Colloid Solutions about?

**Background:** Intravascular volume expansion is followed by loss of fluid from the circulation. The extravasation of albumin in this readjustment is insufficiently known. **Methods:** Twelve male volunteers participated, each in three separate sessions, in a controlled, randomised, open fashion. They received one of the following: albumin 40 g/L,(7.1 mL/kg, i.e. 500 mL per 70 kg); Ringer's acetate (21.4 mL/kg), or dextran 30 g/L (7.1 mL/kg). The fluids were infused during 30 min and the subjects were followed for 180 min. ECG, arterial oxygen saturation and non‐invasive arterial pressure were recorded. Haemoglobin, haematocrit, serum albumin and osmolality, plasma colloid osmotic pressure and hyaluronan concentration were determined in venous samples. **Results:** The serum albumin concentration decreased (__P__ < 0.05, anova) following Ringer's acetate or dextran, whereas serum osmolality was unchanged in all groups. The colloid osmotic pressure decreased (__P__ < 0.05) after the Ringer solution. The blood volume increase was estimated from the decrease in haemoglobin concentration and did not differ between the three fluids. The cumulated extravasation of albumin was largest fo

Who reads Albumin Extravasation and Tissue Washout of Hyaluronan After Plasma Volume Expansion with Crystalloid or Hypooncotic Colloid Solutions?

It is typically read by researchers, students, and practitioners in Medicine.

Author
S. Berg; M. Golster; B. Lisander
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0001-5172)
Published
2002
Language
EN
Field
Medicine (Health Sciences)

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