Can I read Notch Signaling Pathway in Pancreatic Tumorigenesis on EtoBox?

Notch Signaling Pathway in Pancreatic Tumorigenesis by Wen-Cheng Chung; Keli Xu is a book available to read on EtoBox.

What is Notch Signaling Pathway in Pancreatic Tumorigenesis about?

signaling, and its functional significance in PDAC has begun to emerge. Beyond its impact on tumor cells, Notch signaling is an important regulator of the components of pancreatic tumor microenvironment, including blood vasculature, stellate cells, fibroblasts, and immune cells. Finally, Notch may act as a tumor suppressor in pancreatic neuroendocrine tumor, the second most common pancreatic neoplasm with the incidence on rise. This review summarizes the research on the complex roles of Notch signaling in pancreatic tumorigenesis and the development of potential Notch-targeting therapies for pancreatic cancer.

Author

Wen-Cheng Chung; Keli Xu

Publisher

Academic Press, an imprint of Elsevier

Published

2023

Language

EN

ISBN

9780443133541

Subjects

Science, Medical, Biology