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Role of Renal Replacement Therapy in Patients with Type 1 Hepatorenal Syndrome Receiving Combination Treatment of Vasoconstrictor Plus Albumin by Zhiwei Zhang; Geetha Maddukuri; Navin Jaipaul; Cindy X. Cai is a Medicine article available to read on EtoBox.

What is Role of Renal Replacement Therapy in Patients with Type 1 Hepatorenal Syndrome Receiving Combination Treatment of Vasoconstrictor Plus Albumin about?

## Purpose: Utilization of renal replacement therapy (rrt) in cirrhotic patients has been controversial and is typically dependent on the status of transplantation. a better understanding of the central role for arterial vasodilatation in the pathogenesis of hepatorenal syndrome (hrs) has led to routine use of vasoconstrictors in combination with albumin as a medical therapy for hrs with prolonged patient survival. the role of rrt in hrs patients receiving such treatment, however, has not yet been examined. ## Methods: A total of 80 patients with type 1 hrs who received a combination therapy of vasoconstrictors and albumin were enrolled into a retrospective cohort study. the effects of rrt status on clinical outcome were analyzed. ## Results: Both short-term (30 days) and long-term (180 days) survival was similar between rrt and non-rrt groups of patients, but the length of hospital stay was significantly longer among patients in the rrt group, which remain unchanged despite adjustment of status for liver transplantation. ## Conclusions: Based on our observation, routine use of rrt may not be beneficial in patients with type 1 hrs receiving combination treatment of vasoconstrictor

Who reads Role of Renal Replacement Therapy in Patients with Type 1 Hepatorenal Syndrome Receiving Combination Treatment of Vasoconstrictor Plus Albumin?

Author

Zhiwei Zhang; Geetha Maddukuri; Navin Jaipaul; Cindy X. Cai

Published

2015

Language

EN

Field

Medicine (Health Sciences)