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Low frequency vibrations and structural characterization of a murine IgG2a monoclonal antibody studied by Raman and IR spectroscopies by M. Picquart; E. Haro-Poniatowski; J. F. Morhange; M. Jouanne; M. Kanehisa is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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The Raman and ir spectra of a murine IgG2a monoclonal antibody molecule are reported. In accordance with previous studies on immunoglobulins, the secondary structure is predominantly of the ␤-sheet type. The low frequency region of the Raman spectrum was also analyzed in detail. A structured band with two maxima near 43 and 94 cm Ϫ1 was observed. This band has been attributed to vibrations of elastic body. The results are interpreted using a simple elastic model.

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Author

M. Picquart; E. Haro-Poniatowski; J. F. Morhange; M. Jouanne; M. Kanehisa

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0006-3525)

Published

2000

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)