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Low-Flux Versus High-Flux Synthetic Dialysis Membrane in Acute Renal Failure: Prospective Randomized Study by Jadranka Buturović Ponikvar; Rina R. Rus; Rajko B. Kenda; Andrej F. Bren; Rafael R. Ponikvar is a Medicine article available to read on EtoBox.

What is Low-Flux Versus High-Flux Synthetic Dialysis Membrane in Acute Renal Failure: Prospective Randomized Study about?

**Abstract:** The influence of dialyzer membrane on the morbidity and mortality of patients with acute renal failure remains a matter of debate. The aim of the prospective randomized clinical study was to assess the influence of the flux of a synthetic dialyzer membrane on patients' survival rate, restitution of renal function, and duration of hemodialysis treatment of patients with acute renal failure as a part of multiorgan failure. Seventy‐two patients treated in intensive care units of the University Medical Center Ljubljana were randomized according to the dialyzer used throughout the duration of hemodialysis treatment. There were 38 patients in the low‐flux group (dialyzer F6, low‐flux polysuphone, Fresenius, Bad Homburg, Germany) and 34 patients in the high‐flux group (dialyzer Filtral 12, sulphonated high‐flux polyacrylonitrile, Hospal, Industrie Meyzieu, France). Both groups were balanced in terms of sex, age, APACHE II score, oliguria before dialysis, cause of acute renal failure, innotropic support, mechanical ventilation, and the number of failing organs. The patients' survival rate was 18.7% in the low‐flux group and 20.6% in the high‐flux group. Ten patients (26.3%) r

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Author
Jadranka Buturović Ponikvar; Rina R. Rus; Rajko B. Kenda; Andrej F. Bren; Rafael R. Ponikvar
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0160-564X)
Published
2001
Language
EN
Field
Medicine (Health Sciences)

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