Can I read Neutrophil Biology in Injuries and Diseases of the Central and Peripheral Nervous Systems on EtoBox?

Neutrophil Biology in Injuries and Diseases of the Central and Peripheral Nervous Systems by Brian M. Balog; Anisha Sonti; Richard E. Zigmond is a Neuroscience article available to read on EtoBox.

What is Neutrophil Biology in Injuries and Diseases of the Central and Peripheral Nervous Systems about?

The role of inflammation in nervous system injury and disease is attracting increased attention. Much of that research has focused on microglia in the central nervous system (CNS) and macrophages in the peripheral nervous system (PNS). Much less attention has been paid to the roles played by neutrophils. Neutrophils are part of the granulocyte subtype of myeloid cells. These cells, like macrophages, originate and differentiate in the bone marrow from which they enter the circulation. After tissue damage or infection, neutrophils are the first immune cells to infiltrate into tissues and are directed there by specific chemokines, which act on chemokine receptors on neutrophils. We have reviewed here the basic biology of these cells, including their differentiation, the types of granules they contain, the chemokines that act on them, the subpopulations of neutrophils that exist, and their functions. We also discuss tools available for identification and further study of neutrophils. We then turn to a review of what is known about the role of neutrophils in CNS and PNS diseases and injury, including stroke, Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, spinal

Who reads Neutrophil Biology in Injuries and Diseases of the Central and Peripheral Nervous Systems?

Author

Brian M. Balog; Anisha Sonti; Richard E. Zigmond

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Neuroscience (Life Sciences)