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Can I read Contrast-enhanced Mammography in the Assessment of Residual Disease After Neoadjuvant Treatment on EtoBox?
Contrast-enhanced Mammography in the Assessment of Residual Disease After Neoadjuvant Treatment by Molly P. Hogan; Joao V. Horvat; Dara S. Ross; Varadan Sevilimedu; Maxine S. Jochelson; Laurie J. Kirstein; Shari B. Goldfarb; Christopher E. Comstock; Janice S. Sung is a Medicine article available to read on EtoBox.
What is Contrast-enhanced Mammography in the Assessment of Residual Disease After Neoadjuvant Treatment about?
Purpose To investigate the utility of contrast-enhanced mammography (CEM) as an alternative to breast MRI for the evaluation of residual disease after neoadjuvant treatment (NAT). Methods This prospective study enrolled consecutive women undergoing NAT for breast cancer from July 2017-July 2019. Breast MRI and CEM exams performed after completion of NAT were read independently by two breast radiologists. Residual disease and lesion size on MRI and CEM recombined (RI) and low-energy images (LEI) were compared. Histopathology was considered the reference standard. Statistical analysis was performed using McNemar's and Leisenring's tests. Multiple comparison adjustment was made using Bonferroni procedure. Lesion sizes were correlated using Kendall's tau coefficient. Results There were 110 participants with 115 breast cancers. Residual disease (invasive cancer or ductal carcinoma in situ) was detected in 83/115 (72%) lesions on pathology, 71/115 (62%) on MRI, 55/115 (48%) on CEM RI, and 75/115 (65%) on CEM LEI. When using multiple comparison adjustment, no significant differences were detected between MRI combined with CEM LEI and CEM RI combined with CEM LEI, in terms of accuracy (MRI
Who reads Contrast-enhanced Mammography in the Assessment of Residual Disease After Neoadjuvant Treatment?
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- Author
- Molly P. Hogan; Joao V. Horvat; Dara S. Ross; Varadan Sevilimedu; Maxine S. Jochelson; Laurie J. Kirstein; Shari B. Goldfarb; Christopher E. Comstock; Janice S. Sung
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)