Can I read Prediction of extubation outcome in mechanically ventilated patients: Development and validation of the Extubation Predictive Score (ExPreS) on EtoBox?

Prediction of extubation outcome in mechanically ventilated patients: Development and validation of the Extubation Predictive Score (ExPreS) by Antuani Rafael Baptistella; Laura Maito Mantelli; Leandra Matte; Maria Eduarda da Rosa Ulanoski Carvalho; João Antonio Fortunatti; Iury Zordan Costa; Felipe Gabriel Haro; Vanda Laís de Oliveira Turkot; Shaline Ferla Baptistella; Diego de Carvalho; João Rogério Nunes Filho is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Prediction of extubation outcome in mechanically ventilated patients: Development and validation of the Extubation Predictive Score (ExPreS) about?

Despite the best efforts of intensive care units (ICUs) professionals, the extubation failure rates in mechanically ventilated patients remain in the range of 5%–30%. Extubation failure is associated with increased risk of death and longer ICU stay. This study aimed to identify respiratory and non-respiratory parameters predictive of extubation outcome, and to use these predictors to develop and validate an “Extubation Predictive Score (ExPreS)” that could be used to predict likelihood of extubation success in patients receiving invasive mechanical ventilation (IMV). Derivation cohort was composed by patients aged ≥18 years admitted to the ICU and receiving IMV through an endotracheal tube for >24 hours. The weaning process followed the established ICU protocol. Clinical signs and ventilator parameters of patients were recorded during IMV, in the end phase of weaning in pressure support ventilation (PSV) mode, with inspiratory pressure of 7 cm H~2~O over the PEEP (positive end expiratory pressure). Patients who tolerated this ventilation were submitted to spontaneous breathing trial (SBT) with T-tube for 30 minutes. Those who passed the SBT and a subsequent cuff-leak test were extu

Who reads Prediction of extubation outcome in mechanically ventilated patients: Development and validation of the Extubation Predictive Score (ExPreS)?

Author

Antuani Rafael Baptistella; Laura Maito Mantelli; Leandra Matte; Maria Eduarda da Rosa Ulanoski Carvalho; João Antonio Fortunatti; Iury Zordan Costa; Felipe Gabriel Haro; Vanda Laís de Oliveira Turkot; Shaline Ferla Baptistella; Diego de Carvalho; João Rogério Nunes Filho

Publisher

Public Library of Science (PLoS)

Published

2021

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)