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Transcranial Doppler Assessment of Cerebrovascular Reactivity in Symptomatic and Asymptomatic Severe Carotid Stenosis by Mauro Silvestrini; Elio Troisi; Maria Matteis; Letizia M. Cupini; Carlo Caltagirone is a Medicine article available to read on EtoBox.
What is Transcranial Doppler Assessment of Cerebrovascular Reactivity in Symptomatic and Asymptomatic Severe Carotid Stenosis about?
__Background and Purpose__ Some studies have suggested a link between impaired cerebral hemodynamics and stroke in patients with carotid stenosis. The aim of this study was to assess the effects of severe carotid stenosis on cerebrovascular reactivity and the possible changes after endarterectomy. __Methods__ Using bilateral transcranial Doppler ultrasound, we studied the changes of flow velocity after hypercapnia in the middle cerebral arteries of 10 control subjects and 24 patients (13 symptomatic and 11 asymptomatic) with unilateral severe carotid stenosis before and after endarterectomy. Cerebrovascular reactivity was evaluated with the breath-holding index (BHI). __Results__ Before endarterectomy, BHI (mean value±SD) was significantly lower ( __P__ <.001) in the stenotic side of symptomatic patients (0.40±0.2) than in control subjects (1.12±0.3), the stenotic side of asymptomatic patients (0.80±0.4), and the normal side of both symptomatic (0.93±0.3) and asymptomatic (1.03±0.2) patients. On the other hand, no significant difference in BHI was detected in control subjects, on the normal side of symptomatic and asymptomatic patients, and the stenotic side of asymptomatic patient
Who reads Transcranial Doppler Assessment of Cerebrovascular Reactivity in Symptomatic and Asymptomatic Severe Carotid Stenosis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mauro Silvestrini; Elio Troisi; Maria Matteis; Letizia M. Cupini; Carlo Caltagirone
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)