Can I read A Study of the Relation of Exposure to Quinolones and Suicidal Behaviour on EtoBox?

A Study of the Relation of Exposure to Quinolones and Suicidal Behaviour by Susan S. Jick; Catherine Vasilakis; Carlos Martinez; Hershel Jick is a Medicine article available to read on EtoBox.

What is A Study of the Relation of Exposure to Quinolones and Suicidal Behaviour about?

## Aims: To investigate the concern, raised by spontaneous reports received by the german regulatory authorities, that use of quinolone antibiotics may increase the risk for suicide and other suicidal behaviours. ## Methods: We carried out a nested case-control study using the general practice research database (gprd). we compared the risk of suicidal behaviours among users of quinolones, other antibiotics and no antibiotics. ## Results: From january 1, 1991 through april 30, 1995 we identified 348 cases of suicide, attempted suicide, or suicidal ideation and 808 controls. compared with controls, cases who had received a prescription for a quinolone in the 30 days prior to the event had an adjusted relative risk (rr) estimate of 1.5 (95% ci 0.4-6.3) for any suicidal behaviour. cases who had filled a prescription for a quinolone in the 31 to 180 days prior to their event had an adjusted rr estimate of 0.8 (95% ci 0.4-1.7) compared with controls. cases who used other antibiotics in the 30 days prior to the event conferred an adjusted rr estimate of 1.1 (95% ci 0.6-2.2), and 0.9 (95% ci 0.6-1.3) for exposure in the 31 to 180 days prior to the event. the results were not materially dif

Who reads A Study of the Relation of Exposure to Quinolones and Suicidal Behaviour?

Author

Susan S. Jick; Catherine Vasilakis; Carlos Martinez; Hershel Jick

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0306-5251)

Published

1998

Language

EN

Field

Medicine (Health Sciences)