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Data Mining in Bioinformatics (Advanced Information and Knowledge Processing) by Jason T. L. Wang; Mohammed J. Zaki; Hannu Toivonen; Dennis Shasha is a nonfiction available to read on EtoBox.

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8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunctionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erenttissues,its3Dstructureandactivesites,itsfunctionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins

Who reads Data Mining in Bioinformatics (Advanced Information and Knowledge Processing)?

Author

Jason T. L. Wang; Mohammed J. Zaki; Hannu Toivonen; Dennis Shasha

Publisher

Springer-Verlag London Ltd

Published

2005

Language

EN

ISBN

9788181285324

Category

nonfiction

Subjects

Business, Programming, Computer Science