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Randomised Controlled Trial Comparing Preoperative Carbohydrate Loading with Standard Fasting in Paediatric Anaesthesia by Tudor-Drobjewski, B.A.; Marhofer, P.; Kimberger, O.; Huber, W.D.; Roth, G.; Triffterer, L. is a Medicine article available to read on EtoBox.

What is Randomised Controlled Trial Comparing Preoperative Carbohydrate Loading with Standard Fasting in Paediatric Anaesthesia about?

## Background: Preoperative fasting is a major cause of perioperative discomfort in paediatric anaesthesia and leads to postoperative insulin resistance, thus potentially enhancing the inflammatory response to surgery. addressing these problems by preoperative carbohydrate intake has not been a well-defined approach in children. ## Methods: We randomised 120 children scheduled for gastroscopy under general anaesthesia to either a control group of standard preoperative fasting or a study group receiving a carbohydrate beverage (preopTM; nutricia, erlangen, germany). their stomach contents were aspirated endoscopically, and the volume and ph measured. perioperative discomfort was evaluated using, among other parameters, an observational pain scale in ≤4-yr-olds and a vas in >4-yr-olds. the investigators doing the endoscopies and outcome evaluations were blinded to the study group allocation. ## Results: Compared with fasting, carbohydrate loading was associated with significantly less gastric content (p=0.01), fewer patients experiencing postoperative nausea (p=0.028), with no significant difference in postoperative vomiting. high preoperative vas scores (>5) were recorded for only o

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Author
Tudor-Drobjewski, B.A.; Marhofer, P.; Kimberger, O.; Huber, W.D.; Roth, G.; Triffterer, L.
Publisher
Oxford University Press; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0007-0912)
Published
2018
Language
EN
Field
Medicine (Health Sciences)

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