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Can I read Recent Developments in the Identification and Biosynthesis of Antitumor Drugs Derived from Microorganisms on EtoBox?
Recent Developments in the Identification and Biosynthesis of Antitumor Drugs Derived from Microorganisms by Qi Gao; Sizhe Deng; Tianyu Jiang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Recent Developments in the Identification and Biosynthesis of Antitumor Drugs Derived from Microorganisms about?
Secondary metabolites in microorganisms represent a resource for drug discovery and development. In particular, microbial-derived antitumor agents are in clinical use worldwide. Herein, we provide an overview of the development of classical antitumor drugs derived from microorganisms. Currently used drugs and drug candidates are comprehensively described in terms of pharmacological activities, mechanisms of action, microbial sources, and biosynthesis. We further discuss recent studies that have demonstrated the utility of gene-editing technologies and synthetic biology tools for the identification of new gene clusters, expansion of natural products, and elucidation of biosynthetic pathways. This review summarizes recent progress in the discovery and development of microbial-derived anticancer compounds with emphasis on biosynthesis.
Who reads Recent Developments in the Identification and Biosynthesis of Antitumor Drugs Derived from Microorganisms?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Qi Gao; Sizhe Deng; Tianyu Jiang
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)