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Can I read Wound Infusion with Local Anaesthesia After Laparotomy: a Randomized Controlled Trial on EtoBox?

Wound Infusion with Local Anaesthesia After Laparotomy: a Randomized Controlled Trial by Louis William Wang, Shing Wai Wong, Philip John Crowe, Kok Eng Khor, Grazyna Jastrzab, Andrew David Parasyn, William Robert Walsh is a nonfiction available to read on EtoBox.

What is Wound Infusion with Local Anaesthesia After Laparotomy: a Randomized Controlled Trial about?

## Abstract **Background:** The use of a continuous local anaesthesia infusion after laparotomy may reduce opioid requirements and facilitate earlier return of bowel function, independent mobilization and hospital discharge. **Methods:** We performed a double‐blinded, randomized controlled trial on 55 patients who underwent laparotomy. Patients were randomly allocated to receive a continuous infusion of either 0.2% ropivacaine or normal saline into their midline abdominal wound at the fascial level. The end points of the study were: total opioid requirements at 24 and 48 h; time to first flatus, bowel movement and independent ambulation; length of hospital stay; complications; and daily mean patient‐reported pain scores at rest and movement. **Results:** The two treatment groups were well controlled for factors that influence analgesia requirements, including age, weight, length of wound incision and type of operation. Patients allocated to ropivacaine infusion used, on average, 32 mg less morphine at 48 h (95% confidence interval 7, 57; __P__= 0.01). This was highly statistically significant after adjusting for age, gender and type of operation (__P__= 0.0006). Ropivacaine infusio

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Common subject areas: history, science, philosophy, social sciences.

Author
Louis William Wang, Shing Wai Wong, Philip John Crowe, Kok Eng Khor, Grazyna Jastrzab, Andrew David Parasyn, William Robert Walsh
Publisher
John Wiley and Sons; Blackwell Publishing; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1445-1433)
Published
2010
Language
EN
Category
nonfiction

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