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Extranodal non-Hodgkin's lymphoma of the head and neck. A clinicopathologic study in the kyoto-nara area of japan by Nobuko Shima; Yoichiro Kobashi; Kazushige Tsutsui; Katsuhiko Ogawa; Shunzo Maetani; Yasuaki Nakashima; Kunio Ichijima; Hirohiko Yamabe is a scholarly article available to read on EtoBox.

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The clinicopathologic features of 114 Japanese patients with extranodal non-Hodgkin's lymphoma of the head and neck region were analyzed. The median age was 60.5 years and the ma1e:female ratio was 1.5:l. The most common site of involvement was Waldeyer's ring, followed by the oral cavity, thyroid gland, paranasal sinuses, nasal cavity, and larynx. Seventy-five percent of the patients were in Stage I or Stage I1 at admission. Histologically, diffuse lymphoma accounted for 94% and follicular lymphoma for 6% of cases. The histologic grade according to the Working Formulation System of the National Cancer Institute was low in 11%, intermediate in and high in 14% of cases. Immunohistochemical study showed that the majority of the cases were of B-cell type and only 13 cases (11%) were of the T-cell type. Peripheral T-cell lymphomas (eight cases) mainly occurred in the nasopharynx and nasal cavity, whereas four of five thymic T-cell lymphomas were found in the palatine tonsil. The over-all !&year survival rate was 54%, and the factors affecting survival were sex, histologic grade, T/B phenotype, clinical stage, and the site of initial presentation. Five-year survival with nasal cavity an

Author

Nobuko Shima; Yoichiro Kobashi; Kazushige Tsutsui; Katsuhiko Ogawa; Shunzo Maetani; Yasuaki Nakashima; Kunio Ichijima; Hirohiko Yamabe

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1990

Language

EN