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Th 17 Cells: Role in Inflammation and Autoimmune Disease (Progress in Inflammation Research) by Bernhard Ryffel Valerie Quesniaux; Bernhard Ryffel; Franco Di Padova is a nonfiction available to read on EtoBox.

What is Th 17 Cells: Role in Inflammation and Autoimmune Disease (Progress in Inflammation Research) about?

The Il-17 Cytokines Represent A Novel Family Of Cytokines, Which Defines A New Effector T Cell, The Th17 Cell, And Extend The Th1-th2 Paradigm. Th17 Cells In Part Co-express At Least Il-17a And Il-17f, Il-21 And Il-22. Il-17 A/f Are Produced By T Cells ( And ), Inkt Cells, And Possibly Neutrophils, Dendritic Cells And Paneth Cells. The Regulation Of Il-17 Family Member’s Expression, And The Identification Of Effector Mechanisms Are An Area Of Intense Current Research. Recognized Regulators Of Il-17a Expression Include The Nuclear Receptor Ror T, Proinflammatory Cyt- Ines Such As Il-1, Il-6 With Tgf- , Il-21, Il-23 Il-25 In The Absence Of Ifn- And Il-4, Which Are Discussed. Recent Data Suggest That Il-17a May Have A Dual Fu- Tion – Pro-inflammatory And Anti-inflammatory- Suggesting That Il-17a May Also Contribute To Terminate Inflammation. Further, A Reciprocal Regulation Of Th17 And Regulatory T Cells Including The Role Of Retinoic Acid And Tgf- Is Discussed. The Discovery That Patients With Rheumatoid Arthritis, Allergic Disorders, Psor- Sis And Inflammatory Bowel Disease Express Il-17a Generated Interest In The Medical Community And Instigated A Flurry Of Experimental Research On

Who reads Th 17 Cells: Role in Inflammation and Autoimmune Disease (Progress in Inflammation Research)?

Author

Bernhard Ryffel Valerie Quesniaux; Bernhard Ryffel; Franco Di Padova

Publisher

Birkhäuser Basel : Imprint: Birkhäuser

Published

2009

Language

EN

ISBN

9783764386801

Category

nonfiction

Subjects

Medical, Science, Medicine