About this document
Gene Expression Regulation by Fatty Acids by mueen hashmi is a document available to read on EtoBox.
The document discusses how fatty acids regulate gene expression through nuclear receptors and other transcription factors. It describes how non-esterified fatty acids or their CoA derivatives can directly activate nuclear receptors like PPAR, LXR, and HNF-4α by binding to them. This causes changes in transcription of target genes. Fatty acids can also indirectly affect gene expression by changing the abundance or activity of other transcription factors such as SREBP and ChREBP. The key nuclear receptors tha
- Author
- mueen hashmi
- Language
- EN