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Can I read A Study to Correlate Histopathology, Biochemical Marker and Immunohistochemical Expression of Sex-steroid Receptors in Prostatic Growth on EtoBox?
A Study to Correlate Histopathology, Biochemical Marker and Immunohistochemical Expression of Sex-steroid Receptors in Prostatic Growth by Sukla Naskar; Soumya Kanti Kundu; Nirmal Kumar Bhattacharyya; Pranab Kumar Bhattacharyya; Anup Kumar Kundu is a Medicine article available to read on EtoBox.
What is A Study to Correlate Histopathology, Biochemical Marker and Immunohistochemical Expression of Sex-steroid Receptors in Prostatic Growth about?
Prostate gland is a fibromusculoglandular structure situated at the neck of urinary bladder. So, enlargement or growth of prostate due to nodular hyperplasia (NHP) or prostatic intraepithelial neoplasia (PIN) or adenocarcinoma may give rise to bladder outlet obstruction. Malignant growth i.e., PIN or adenocarcinoma cases are associated with increased blood level of prostate-specific antigen (PSA) and increased expression of different sex-steroid receptors because the growth is dependent on the interactions of androgen, progesterone and estrogen. The aim of our study is to correlate the histopathology, PSA levels and expression of different sex-steroid receptors by immunohistochemistry in different prostatic growth lesions. Among the total 50 cases received, inclusive of transurethral resection of prostate (TURP), transrectal ultrasound-guided biopsy and radical prostatectomy, 34 cases were diagnosed as NHP, 4 cases as PIN and 12 cases as adenocarcinoma histopathologically. Serum PSA values above 10 ng/ml were seen in 2 cases of PIN and 11 cases of adenocarcinoma and none of NHP. Estrogen receptor (ER) () expressions were negative in all cases. Progesterone receptor (PR) expressions
Who reads A Study to Correlate Histopathology, Biochemical Marker and Immunohistochemical Expression of Sex-steroid Receptors in Prostatic Growth?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sukla Naskar; Soumya Kanti Kundu; Nirmal Kumar Bhattacharyya; Pranab Kumar Bhattacharyya; Anup Kumar Kundu
- Publisher
- Georg Thieme Verlag KG
- Published
- 2014
- Language
- EN
- Field
- Medicine (Health Sciences)