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The Impact of Obesity in Renal Transplantation: an Analysis of Paired Cadaver Kidneys by Shinji Yamamoto; Eileen Hanley; Amy B Hahn; Andrew Isenberg; T Paul Singh; Dennis Cohen; David J Conti is a Medicine article available to read on EtoBox.

What is The Impact of Obesity in Renal Transplantation: an Analysis of Paired Cadaver Kidneys about?

Background: Previous studies indicate that obesity is a risk factor in renal transplantation. However, these analyses did not control for variable donor factors that may strongly influence outcome. To control for donor variables such as age, cause of death, procurement techniques, preservation methods, cold ischaemia time and implantation technique, we analysed patient and graft survival in recipients of paired kidneys, derived from the same procurement procedure, preserved in the same manner, subjected to similar cold ischaemia time and implanted by the same surgical team. Between June 1992 and August 1999, 28 procurement procedures provided kidneys which were transplanted into one obese and one non‐obese recipient. Body mass index (BMI) was calculated as kg/m^2^. Recipients were classified as obese (BMI > 30) or non‐obese (BMI < 30). Immunotherapy for all recipients consisted of a triple therapy regimen of cyclosporine or prograf, azathioprine or cellcept, and prednisone. Patients with delayed graft function (DGF), defined as the need for dialysis within 72 h of the transplant procedure, were treated with anti‐thymocyte globulin (ATG) or thymoglobulin (TMG) induction for 5–7 d. T

Who reads The Impact of Obesity in Renal Transplantation: an Analysis of Paired Cadaver Kidneys?

Author

Shinji Yamamoto; Eileen Hanley; Amy B Hahn; Andrew Isenberg; T Paul Singh; Dennis Cohen; David J Conti

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0902-0063)

Published

2002

Language

EN

Field

Medicine (Health Sciences)