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This study investigates the molecular characteristics of tumors of purported specialized prostatic stromal origin, including prostatic stromal sarcomas (PSS) and stromal tumors of uncertain malignant potential (STUMP). Using next-generation DNA and RNA sequencing on 25 cases, the research reveals significant molecular heterogeneity and identifies non-recurring gene fusions associated with other mesenchymal tumors. The findings suggest that these tumors may not represent a single diagnostic entity, highlight

Author

Salaash1

Language

EN