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Signal in the Noise: Temporal Variation in Exponentially Growing Populations by Jones, Eric W.; Derrick, Joshua; Nisbet, Roger M.; Ludington, Will; Sivak, David A. is a scholarly article available to read on EtoBox.

What is Signal in the Noise: Temporal Variation in Exponentially Growing Populations about?

In exponential population growth, variability in the timing of individual division events and environmental factors (including stochastic inoculation) compound to produce variable growth trajectories. In several stochastic models of exponential growth we show power-law relationships that relate variability in the time required to reach a threshold population size to growth rate and inoculum size. Population-growth experiments in E. coli and S. aureus with inoculum sizes ranging between 1 and 100 are consistent with these relationships. We quantify how noise accumulates over time, finding that it encodes -- and can be used to deduce -- information about the early growth rate of a population.

Author

Jones, Eric W.; Derrick, Joshua; Nisbet, Roger M.; Ludington, Will; Sivak, David A.

Published

2023

Language

EN