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Dangerous Liaisons: How Helminths Manipulate the Intestinal Epithelium by Danielle Karo-Atar; Alex Gregorieff; Irah L. King is a Medicine article available to read on EtoBox.

What is Dangerous Liaisons: How Helminths Manipulate the Intestinal Epithelium about?

Intestinal helminths remain highly pervasive throughout the animal kingdom by modulating multiple aspects of the host immune response. The intestinal epithelium functions as a physical barrier as well as a sentinel innate immune tissue with the ability to sense and respond to infectious agents. Although helminths form intimate interactions with the epithelium, comprehensive knowledge about host–helminth interactions at this dynamic interface is lacking. In addition, little is known about the ability of helminths to directly shape the fate of this barrier tissue. Here, we review the diverse pathways by which helminths regulate the epithelium and highlight the emerging field of direct helminth regulation of intestinal stem cell (ISC) fate and function.

Who reads Dangerous Liaisons: How Helminths Manipulate the Intestinal Epithelium?

Author

Danielle Karo-Atar; Alex Gregorieff; Irah L. King

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)