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Dietary Polysaccharides from Guavira Pomace, a Co-product from the Fruit Pulp Industry, Display Therapeutic Application in Gut Disorders by Natalia Mulinari Turin de Oliveira; Bruna Barbosa da Luz; Vanessa Suzane Schneider; Humberto Barbosa da Costa Filho; Paulo Sérgio de Araujo Sousa; Maria Fernanda de Paula Werner; Marcellus Henrique Loiola Ponte de Souza; Jefferson Almeida Rocha; Lucas Antonio Duarte Nicolau; Lucimara Mach Côrtes Cordeiro; Daniele Maria-Ferreira is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Dietary Polysaccharides from Guavira Pomace, a Co-product from the Fruit Pulp Industry, Display Therapeutic Application in Gut Disorders about?

Inflammatory bowel disease (IBD) includes two distinct diseases: Crohn's disease (CD) and ulcerative colitis (UC). IBD is a chronic systemic disease of the gastrointestinal tract, characterized by an inflammatory process. The mechanisms by which diseases develop are still unknown, but it is known that it results from a complex interaction between genetic variability, the host's immune system, and environmental factors. One of the main complaints of patients is abdominal pain, which may be associated with the release of inflammatory mediators, changes in the normal motility of the digestive tract, and increased intestinal permeability. Currently available drugs for abdominal pain are not satisfactory, therefore, it is extremely necessary to seek new therapeutic options for the treatment of abdominal pain. Polysaccharides extracted from fruits have attracted interest, as these molecules protect the intestinal mucosa and promote wound healing, attenuating inflammation, pain, and altered intestinal motility. In this study, we investigated the ability of pectic polysaccharides obtained from guavira pomace, named CPW to reduce visceral hypersensitivity, regulate intestinal motility, and

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Author

Natalia Mulinari Turin de Oliveira; Bruna Barbosa da Luz; Vanessa Suzane Schneider; Humberto Barbosa da Costa Filho; Paulo Sérgio de Araujo Sousa; Maria Fernanda de Paula Werner; Marcellus Henrique Loiola Ponte de Souza; Jefferson Almeida Rocha; Lucas Antonio Duarte Nicolau; Lucimara Mach Côrtes Cordeiro; Daniele Maria-Ferreira

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)