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Can I read Web-accessible Proteome Databases for Microbial Research on EtoBox?
Web-accessible Proteome Databases for Microbial Research by Klaus-Peter Pleißner; Till Eifert; Sven Buettner; Frank Schmidt; Martina Boehme; Thomas F. Meyer; Stefan H. E. Kaufmann; Peter R. Jungblut is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Web-accessible Proteome Databases for Microbial Research about?
## Abstract The analysis of proteomes of biological organisms represents a major challenge of the post‐genome era. Classical proteomics combines two‐dimensional electrophoresis (2‐DE) and mass spectrometry (MS) for the identification of proteins. Novel technologies such as isotope coded affinity tag (ICAT)‐liquid chromatography/mass spectrometry (LC/MS) open new insights into protein alterations. The vast amount and diverse types of proteomic data require adequate web‐accessible computational and database technologies for storage, integration, dissemination, analysis and visualization. A proteome database system (http://www.mpiib‐berlin.mpg.de/2D‐PAGE) for microbial research has been constructed which integrates 2‐DE/MS, ICAT‐LC/MS and functional classification data of proteins with genomic, metabolic and other biological knowledge sources. The two‐dimensional polyacrylamide gel electrophoresis database delivers experimental data on microbial proteins including mass spectra for the validation of protein identification. The ICAT‐LC/MS database comprises experimental data for protein alterations of mycobacterial strains BCG __vs.__ H37Rv. By formulating complex queries within a funct
Who reads Web-accessible Proteome Databases for Microbial Research?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Klaus-Peter Pleißner; Till Eifert; Sven Buettner; Frank Schmidt; Martina Boehme; Thomas F. Meyer; Stefan H. E. Kaufmann; Peter R. Jungblut
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley; Research Square (ISSN 1615-9853)
- Published
- 2004
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)