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Anorectal Dysfunction in Multiple Sclerosis: A Systematic Review by Sanober Nusrat; Elsie Gulick; David Levinthal; Klaus Bielefeldt is a Medicine article available to read on EtoBox.

What is Anorectal Dysfunction in Multiple Sclerosis: A Systematic Review about?

Constipation and fecal incontinence are common in patients with neuromuscular diseases. Despite their high prevalence and potential impact on overall quality of life, few studies have addressed anorectal dysfunction in patients with multiple sclerosis (MS). The goal of this paper is to define the prevalence, pathophysiology, impact, and potential treatment of constipation and incontinence in MS patients. __Methods__. The PubMed database was searched for English language publications between January 1973 and December 2011. Articles were reviewed to assess the definition of the study population, duration, type and severity of MS, sex distribution, prevalence, impact, results of physiologic testing, and treatments. __Results__. The reported prevalence of constipation and fecal incontinence ranged around 40%. Anorectal dysfunction significantly affected patients with nearly 1 in 6 patients limiting social activities or even quitting work due to symptoms. Caregivers listed toileting as a common and significant burden. The only randomized controlled trial showed a marginal improvement of constipation with abdominal massage. All other reports lacked control interventions and only demonstr

Who reads Anorectal Dysfunction in Multiple Sclerosis: A Systematic Review?

Author

Sanober Nusrat; Elsie Gulick; David Levinthal; Klaus Bielefeldt

Publisher

Hindawi Limited

Published

2012

Language

EN

Field

Medicine (Health Sciences)