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Cream Production and Biological in Vivo/in Vitro Activity Assessment of a Novel Boron-based Compound Derived from Quercetin and Phenyl Boronic Acid by Hamdi Temel; Metin Atlan; Abdulselam Ertas; Ismail Yener; Mehmet Akdeniz; Zehra Yazan; Mustafa Abdullah Yilmaz; Zuleyha Doganyigit; Asli Okan; Enes Akyuz is a Environmental Science article available to read on EtoBox.

What is Cream Production and Biological in Vivo/in Vitro Activity Assessment of a Novel Boron-based Compound Derived from Quercetin and Phenyl Boronic Acid about?

Boronic acids constitute an important class of synthetic intermediates due to their high chemical stability, ease of use, moderate organic Lewis acid properties, reduced reactivity profiles and numerous biological activities such as antibacterial and antioxidant. The present study documents the synthesis and characterization of a novel boronic ester compound (3,5,7-trihydroxy-2- (2-phenyl benzo [d] [1,3,2] dioxaborol-5-yl) -4H-chromen-4-a) which was derived from phenyl boronic acid and quercetin. The new boron-based compound was used in the cream formulation after evaluating its antioxidant, antibacterial, anti-enzyme, anticancer activities and electrochemical oxidation behaviour. Furthermore, the cream has been dermatologically and microbiologically tested. Also, histological evaluation of the agent was estimated on multiple rat organs by hematoxylin-eosin staining method. Antioxidant potential of the new compound was tested by ABTS cation radical (IC: 0.11 ± 0.01 μg/mL), DPPH free radical scavenging (IC: 0.14 ± 0.01 μg/mL), and CUPRAC (A: 1.73 ± 0.16 μg/mL) methods, respectively. The compound determined to have a dominant antioxidant activity. In addition, the synthesized compoun

Who reads Cream Production and Biological in Vivo/in Vitro Activity Assessment of a Novel Boron-based Compound Derived from Quercetin and Phenyl Boronic Acid?

It is typically read by researchers, students, and practitioners in Environmental Science.

Author
Hamdi Temel; Metin Atlan; Abdulselam Ertas; Ismail Yener; Mehmet Akdeniz; Zehra Yazan; Mustafa Abdullah Yilmaz; Zuleyha Doganyigit; Asli Okan; Enes Akyuz
Publisher
Elsevier BV
Published
2022
Language
EN
Field
Environmental Science (Physical Sciences)

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