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Muscular Strength Measured Across the Life-course and the Metabolic Syndrome by Brooklyn J. Fraser; Leigh Blizzard; Marie-Jeanne Buscot; Michael D. Schmidt; Terence Dwyer; Alison J. Venn; Costan G. Magnussen is a Medicine article available to read on EtoBox.

What is Muscular Strength Measured Across the Life-course and the Metabolic Syndrome about?

Background and aims Low muscular strength associates with the metabolic syndrome (MetS). However, how muscular strength measured at different life stages contribute to the development of MetS is unknown. This study compared the contribution of muscular strength measured in youth, young- and mid-adulthood with MetS in midlife. Methods and results Prospective longitudinal study of 267 Childhood Determinants of Adult Health Study participants who between 1985 and 2019 had measures of muscular strength (dominant grip strength) at three life stages (youth = 9–15 years, young adulthood = 26–36 years, mid-adulthood = 36–49 years) and had their MetS status assessed in mid-adulthood. Bayesian relevant life-course exposure models quantified associations between muscular strength at each life stage with MetS and estimated the maximum accumulated effect of lifelong muscular strength. The contribution of muscular strength at each life stage with MetS was equal (youth = 38%, young adulthood = 28%, mid-adulthood = 34%). A one standard deviation increase in cumulative muscular strength was associated with 46% reduced odds of MetS. Of all MetS components, muscular strength was most strongly negativ

Who reads Muscular Strength Measured Across the Life-course and the Metabolic Syndrome?

Author

Brooklyn J. Fraser; Leigh Blizzard; Marie-Jeanne Buscot; Michael D. Schmidt; Terence Dwyer; Alison J. Venn; Costan G. Magnussen

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)