Can I read Expression of potassium channels during postnatal differentiation of rabbit Müller glial cells on EtoBox?

Expression of potassium channels during postnatal differentiation of rabbit Müller glial cells by A. Bringmann; B. Biedermann; A. Reichenbach is a Neuroscience article available to read on EtoBox.

What is Expression of potassium channels during postnatal differentiation of rabbit Müller glial cells about?

## Abstract The postnatal maturation of Müller glial cells from immature radial glial cells is accompanied by specific changes in the activity of distinct types of K^+^ channels, as shown by whole‐cell and cell‐attached records on freshly isolated cells from retinae of young (postnatal days 1–30, P1–P30) and adult rabbits. (i) The density of inwardly rectifying currents, providing the main K^+^ conductance in adult Müller cells, was very low (0.8 pA/pF) from P1 to P6 but increased rapidly thereafter until a relatively stable level of 11.0 pA/pF was established at P17. (ii) Transient (A‐type) K^+^ currents were expressed in all immature cells at a high density (9.6 pA/pF). After P12, both the percentage of cells with A‐type currents and the peak amplitudes of the currents (2.8 pA/pF) declined. (iii) Delayed rectifying K^+^ currents developed slowly until after P30. (iv) The postnatal maturation of radial glial cells was accompanied by a strong decrease in the activity of large‐conductance, Ca^2+^‐activated K^+^ channels, the open probability of which (measured at the resting membrane potential) decreased from 0.69 at P2–4 to 0.06 at P13–14. The developmental decrease of the activity

Who reads Expression of potassium channels during postnatal differentiation of rabbit Müller glial cells?

Author

A. Bringmann; B. Biedermann; A. Reichenbach

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0953-816X)

Published

1999

Language

EN

Field

Neuroscience (Life Sciences)