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What is Understanding Pharmacokinetics and Dynamics about?

This document discusses several key factors that affect pharmacokinetics in children compared to adults, including differences in absorption, distribution, and metabolism of drugs. Absorption is impacted by differences in gastric pH, gastric emptying, and intestinal transit times in children. Distribution is affected by higher membrane permeability in children, especially in the brain before the blood-brain barrier is fully developed. Metabolism can be impacted by differences in plasma protein binding and l

Author

mebibeg

Language

EN